|
Authors
JOHN E SMITH BSc MSc PhD DSc FIBiol FRSE
Emeritus Professor of Applied Microbiology, University of
Strathclyde
Chief Scientific Officer, MycoBiotech Ltd, Singapore
NEIL J ROWAN BSc MSc PhD MIBiol MIFST
Lecturer, Department of Bioscience, University of Strathclyde
RICHARD SULLIVAN BSc MD PhD
Head of Clinical Programmes, Cancer Research UK
Introduction
Many of the currently
available anti-cancer agents are derived form natural products,
for instance paclitaxel (Taxol), and camptothecin (Hycamtin)
amongst many others. In 2000 Professor Gordon McVie, Director-General
of the Cancer Research Campaign (now Cancer Research UK) and
Professor John Smith of University of Strathclyde met in Glasgow
to discuss the role of medicinal mushrooms in the treatment
of cancer. The CRC had become aware that these natural products
were being used extensively in the Far East as nutriceuticals
(dietary supplements) and as a source for the generation of
pharmaceutical-grade medicines to treat a wide variety of
diseases, including cancer. The substantial range of medicinal
mushroom species from which different bioactive compounds
can be derived suggested that the humble mushroom could be
a source of novel anti-cancer agents.
This monograph is a comprehensive overview of this subject
from the technology of cultivation, extraction and chemistry
of medicinal mushroom bioactive compounds to the clinical
evidence that suggests an important therapeutic role in cancer,
and other major diseases.
Download the monograph
The monograph is available for download on a chapter by chapter
basis as PDF documents. If you don't have a copy of Adobe
Acrobat, you can download a copy from their website at www.adobe.com/products/acrobat/readstep.html.
If you are having difficulty downloading the monograph - some
of the sections are quite large due to high quality images
- please contact Cancer Research UK via the email or phone
details listed below to obtain a CD copy.
- Executive
Summary (33KB)
- Front
page
(13KB)
- Preamble
(16KB)
- Index
(9KB)
- Chapter
1 - Introduction
(37KB)
- Chapter
2 - Nature of fungi with special emphasis on mushrooms
(1,451KB)
- Chapter 3 - Medicinally important mushrooms
- Chapter
4 - Technology of mushroom cultivation
(339KB)
- Chapter
5 - Extraction, development and chemistry of anti-cancer
compounds from medicinal mushrooms
(400KB)
- Chapter
6 - Immunomodulatory activities of mushroom glucans
and polysaccharide-protein complexes in animals and humans
(217KB)
- Chapter
7 - The role of polysaccarides derived from medicinal
mushrooms in cancer
(134KB)
- Chapter
8 - Additional medicinal properties
(85KB)
- Chapter
9 - Regulatory and safety criteria for functional foods
and dietary supplements and pharmaceutical medicines; the
role for medicinal mushrooms
(68KB)
- Chapter
10 - Conclusions
(50KB)
- Appendix
1
(604KB)
- Appendix
2 (13KB)
- Appendix
3 (18KB)
- Biographies
(10KB)
- Acknowledgements
(7KB)
Contacts at Cancer Research UK
For more information email John Smith at E.S.Clements@strath.ac.uk
or contact Richard Sullivan on Tel: 020 7242 0200 or richard.sullivan@cancer.org.uk.
|
